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RI-OR2

CAT: 0931-TP3103-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0931-TP3103-01Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
1219627-58-3
Target
Beta Amyloid
Related Pathways
Neuroscience
Bioactivity
RI-OR2 is a retro-inverso peptide that acts as an amyloid-β (Aβ) oligomerization inhibitor. It binds to fixed β-Amyloid (1-42) monomers and fibrils, with an apparent Kd of 9-12 μM, and also serves as an inhibitor of Aβ (1-42) fibril extension.
Smiles
[C@H](CC1=CC=CC=C1)(NC([C@@H](CC2=CC=CC=C2)NC(CNC([C@@H](CCCNC(=N)N)NC(C)=O)=O)=O)=O)C(N[C@@H](C(N[C@@H](C(N[C@@H](C(NCC(N[C@H](CCCNC(=N)N)C(N)=O)=O)=O)CCCCN)=O)CC(C)C)=O)[C@H](C)C)=O
Molecular Formula
C53H85N17O10
Molecular Weight
1120.35
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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