RI-OR2

• CAS Number :

  1219627-58-3

• Target :

  Beta Amyloid

• Related Pathways :

  Neuroscience

• Bioactivity :

  RI-OR2 is a retro-inverso peptide that acts as an amyloid-? (A?) oligomerization inhibitor. It binds to fixed ?-Amyloid (1-42) monomers and fibrils, with an apparent Kd of 9-12 ?M, and also serves as an inhibitor of A? (1-42) fibril extension.

• Smiles :

  [C@H](CC1=CC=CC=C1)(NC([C@@H](CC2=CC=CC=C2)NC(CNC([C@@H](CCCNC(=N)N)NC(C)=O)=O)=O)=O)C(N[C@@H](C(N[C@@H](C(N[C@@H](C(NCC(N[C@H](CCCNC(=N)N)C(N)=O)=O)=O)CCCCN)=O)CC(C)C)=O)[C@H](C)C)=O

• Molecular Formula :

  C53H85N17O10

• Molecular Weight :

  1120.35

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C