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TGFβRI-IN-5

CAT: 0931-T60931-01Size: 25 mgDry Ice: NoHazardous: No
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CAT#:0931-T60931-01Size:25 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
2541690-15-5
Target
Others, TGF-beta/Smad
Related Pathways
Stem Cells, Others
Bioactivity
TGFβRI-IN-5 (Compound 4b) is a potent TGFβRI inhibitor with an IC50 of 0.08 μM, demonstrating significant anticancer activity by enhancing apoptosis and arresting the G2/M phase of the cell cycle in all tested cell lines[1].
Smiles
N(C(=O)C1=CC=C(N(=O)=O)C=C1)(C(C)=O)C2=C(C(O)=O)C=CC=C2
Molecular Formula
C16H12N2O6
Molecular Weight
328.28
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

Chemical Information

Tgf|ari-IN-5
CAS Number2541690-15-5
PubChem CID138060613
IUPAC Name2-[acetyl-(4-nitrobenzoyl)amino]benzoic acid
Molecular FormulaC16H12N2O6
Molecular Weight328.28
XLogP2.1
Topological Polar Surface Area121
Hydrogen Bond Donor Count1
Hydrogen Bond Acceptor Count6
Rotatable Bond Count3
Heavy Atom Count24
Formal Charge0
Complexity521
SMILES
CC(=O)N(C1=CC=CC=C1C(=O)O)C(=O)C2=CC=C(C=C2)[N+](=O)[O-]
InChI
InChI=1S/C16H12N2O6/c1-10(19)17(14-5-3-2-4-13(14)16(21)22)15(20)11-6-8-12(9-7-11)18(23)24/h2-9H,1H3,(H,21,22)
InChIKey
FJNGYVMTOCTQFD-UHFFFAOYSA-N
Chemical Structure
2D Structure
2D structure of Tgf|ari-IN-5
CAS: 2541690-15-5
CID: 138060613
Formula: C16H12N2O6
MW: 328.28
Interactive 3D Structure
Loading 3D structure...
View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight328.28
XLogP32.1
Hydrogen Bond Donor Count1
Hydrogen Bond Acceptor Count6
Rotatable Bond Count3
Exact Mass328.06953611
Monoisotopic Mass328.06953611
Topological Polar Surface Area121 Ų
Heavy Atom Count24
Formal Charge0
Complexity521
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes

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Alternative Products

CatalogName
HY-147786TGFβRI-IN-5
BA9155-25TGFβRI-IN-3
HY-172108TGFβRI-IN-7
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GTR19212494-01TGFβRI-IN-6
GTR19186040-01TGFβRI-IN-4
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HY-114192TGFβRI-IN-1
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