Products for Research Use Only

S9-CMC1 TFA

CAT: 0931-TP3001-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0931-TP3001-01Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Target
Apoptosis, Histone Demethylase
Related Pathways
Apoptosis, Chromatin/Epigenetic
Bioactivity
S9-CMC1 TFA is a covalent peptide lysine-specific demethylase 1 (LSD1) inhibitor with an IC50 value of 2.53 μM. It selectively targets the active site Cys360 of the enzyme. By inhibiting LSD1 activity, S9-CMC1 TFA elevates H3K4me1 and H3K4me2 levels, inducing G1 cell cycle arrest and apoptosis, thereby suppressing cell proliferation. In addition, S9-CMC1 TFA markedly inhibits tumor growth in A549 xenograft animal models.
Molecular Formula
C97H151F3N32O17S2
Molecular Weight
2158.57
Shipping Conditions
Ice Packs
Storage Temperature
-20°C