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EC-1456

CAT: 0931-TP2840-01Size: 10 mgDry Ice: NoHazardous: No
CAT#:0931-TP2840-01Size:10 mg
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
1602487-16-0
Target
Others|||Antifolate
Related Pathways
Cell Cycle/Checkpoint|||Others
Bioactivity
EC-1456 is a folate-microtubule targeting agent that exhibits significant antiproliferative activity against folate receptor (FR) positive tumors, including models resistant to anticancer drugs. EC-1456 is utilized in cancer research.
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[C@H](C[C@@H](N(C([C@@H](NC(=O)[C@@H]1N(C)CCCC1)[C@H](CC)C)=O)COC(CCC)=O)C(C)C)(OC(C)=O)C2=NC(C(N[C@@H](CC3=CC=C(O)C=C3)C[C@@H](C(NNC(OCCSSC[C@@H](NC([C@@H](NC([C@H](NC([C@@H](NC([C@H](NC([C@@H](NC(CC[C@@H](NC(=O)C4=CC=C(NCC=5N=C6C(NC5)=NC(N)=NC6=O)C=C4)C(O)=O)=O)CCC(NC[C@@H]([C@H]([C@@H]([C@@H](CO)O)O)O)O)=O)=O)CCC(O)=O)=O)CCC(NC[C@@H]([C@H]([C@@H]([C@@H](CO)O)O)O)O)=O)=O)CCC(O)=O)=O)CCC(NC[C@@H]([C@H]([C@@H]([C@@H](CO)O)O)O)O)=O)=O)C(O)=O)=O)=O)C)=O)=CS2
Molecular Formula
C110H165N23O45S3
Molecular Weight
2625.81
Shipping Conditions
Cool pack
Storage Temperature
-20°C

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