GTP-14564

• Target :

  Tyrosine Kinases|||FLT

• Related Pathways :

  Angiogenesis|||Tyrosine Kinase/Adaptors

• Purity :

  0.9981

• Bioactivity :

  GTP-14564 is a novel tyrosine kinase inhibitor that also inhibits wt-FLT3 and ITD-FLT3. GTP-14564 inhibits the growth of interleukin-3-independent Ba/F1 expressing ITD-FLT3 at 3 ? m, whereas a 30-fold higher concentration of GTP-14564 is required to inhibit the FLT3 ligand-dependent growth (wt-FLT3) of Ba/F3 expressing wild-type FLT3. F3 expressing wild-type FLT3 (wt-FLT3) .

• Smiles :

  C12=C(C=3C(O1)=CC=CC3)NN=C2C4=CC=CC=C4

• Molecular Formula :

  C15H10N2O

• Molecular Weight :

  234.25

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C

• CAS Number :

  34823-86-4