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PHM-27 (human) acetate

CAT: 0931-TP1954L-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0931-TP1954L-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Target
CGRP Receptor
Related Pathways
Neuroscience, GPCR/G Protein
Purity
0.992
Bioactivity
PHM-27 (human) acetate is the endogenous peptide product of prepro-VIP (human), an agonist of the calcitonin receptor (EC 50 = 11 nM) . Transgenic mice overexpressing PHM-27 (human) acetate in pancreatic β-islets exhibited enhanced glucose-induced insulin secretion.
Smiles
OC(C=C1)=CC=C1C[C@@H](C(N[C@@H](CC(C)C)C(N[C@@H](CCC(O)=O)C(N[C@@H](CO)C(N[C@@H](CC(C)C)C(N[C@H](C(N)=O)CCSC)=O)=O)=O)=O)=O)NC([C@H](CCCCN)NC([C@H](CCCCN)NC([C@H](C)NC([C@H](CO)NC([C@H](CC(C)C)NC([C@H](CCC(N)=O)NC(CNC([C@H](CC(C)C)NC([C@H](CC(C)C)NC([C@H](CCCCN)NC([C@H](CO)NC([C@@H](NC([C@H](CC(O)=O)NC([C@H](CO)NC([C@H]([C@H](O)C)NC([C@@H](NC([C@H](C(C)C)NC(CNC([C@H](CC(O)=O)NC([C@H](C)NC([C@@H](N)CC2=CN=CN2)=O)=O)=O)=O)=O)CC3=CC=CC=C3)=O)=O)=O)=O)CC4=CC=CC=C4)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O.O=C(C(F)(F)F)O
Molecular Formula
C137H215F3N34O42S
Molecular Weight
3099.44
Shipping Conditions
Ice Packs
Storage Temperature
-20°C