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PHM-27 (human)

CAT: 0931-TP1954Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0931-TP1954Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
87403-73-4
Target
CGRP Receptor
Related Pathways
Neuroscience, GPCR/G Protein
Bioactivity
Endogenous peptide product of human prepro-VIP and analog of porcine PHI-27; potent agonist for the human calcitonin receptor (EC50 = 11 nM) . Transgenic mice expressing the human VIP/PHM 27 gene in pancreatic β-islets display enhanced glucose-induced insulin secretion.
Smiles
[C@@H](CC1=CC=C(O)C=C1)(NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC(CNC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@H](CC2=CC=CC=C2)NC([C@@H](NC([C@@H](NC([C@@H](NC([C@H](CC3=CC=CC=C3)NC([C@@H](NC(CNC([C@@H](NC([C@@H](NC([C@H](CC4=CN=CN4)N)=O)C)=O)CC(O)=O)=O)=O)C(C)C)=O)=O)[C@@H](C)O)=O)CO)=O)CC(O)=O)=O)=O)CO)=O)CCCCN)=O)CC(C)C)=O)CC(C)C)=O)=O)CCC(N)=O)=O)CC(C)C)=O)CO)=O)C)=O)CCCCN)=O)CCCCN)=O)C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@@H](CCSC)C(N)=O)=O)CC(C)C)=O)CO)=O)CCC(O)=O)=O)CC(C)C)=O
Molecular Formula
C135H214N34O40S
Molecular Weight
2985.44
Shipping Conditions
Ice Packs
Storage Temperature
-20°C