AMT-562

CAT: 0931-T9901A-1039-01Size: 1 mgDry Ice: NoHazardous: No
CAT#:0931-T9901A-1039-01Size:1 mg
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PRICE
AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Target
EGFR|||Apoptosis|||Antibody-Drug Conjugates (ADCs) |||Topoisomerase
Related Pathways
Apoptosis|||Antibody-drug Conjugate/ADC Related|||Tyrosine Kinase/Adaptors|||DNA Damage/DNA Repair|||JAK/STAT signaling|||Angiogenesis
Bioactivity
AMT-562 is an antibody-drug conjugate (ADC) composed of a novel anti-HER3 antibody, Ab562, linked to the linker Mc-VC-PAB and the topoisomerase I inhibitor, Exatecan. The ADC's toxic component and linker are represented as MC-VA-PAB-Exatecan. AMT-562 can induce apoptosis and exhibits antitumor activity against pancreatic, esophageal, and gastric cancers.
Shipping Conditions
Cool pack
Storage Temperature
-20°C

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