AMT-562

• Target :

  EGFR|||Apoptosis|||Antibody-Drug Conjugates (ADCs) |||Topoisomerase

• Related Pathways :

  Apoptosis|||Antibody-drug Conjugate/ADC Related|||Tyrosine Kinase/Adaptors|||DNA Damage/DNA Repair|||JAK/STAT signaling|||Angiogenesis

• Bioactivity :

  AMT-562 is an antibody-drug conjugate (ADC) composed of a novel anti-HER3 antibody, Ab562, linked to the linker Mc-VC-PAB and the topoisomerase I inhibitor, Exatecan. The ADC's toxic component and linker are represented as MC-VA-PAB-Exatecan. AMT-562 can induce apoptosis and exhibits antitumor activity against pancreatic, esophageal, and gastric cancers.

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C