Products for Research Use Only

AMT-562 Antibody

CAT: 0013-GTR18712516-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR18712516-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
AMT-562 is an antibody-drug conjugate (ADC) composed of a novel anti-HER3 antibody, Ab562, linked to the linker Mc-VC-PAB and the topoisomerase I inhibitor, Exatecan. The ADC's toxic component and linker are represented as MC-VA-PAB-Exatecan. AMT-562 can induce apoptosis and exhibits antitumor activity against pancreatic, esophageal, and gastric cancers.
Target
Antibody-Drug Conjugates (ADCs), Topoisomerase, EGFR, Apoptosis
Clonality
Polyclonal
Conjugation
Unconjugated
Field of Research
Cardiovascular Research, Cell Biology, Molecular Biology, Signal Transduction
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Notes
For research use only.