NP3-562

CAT: 0931-T87031-01Size: 10 mgDry Ice: NoHazardous: No
CAT#:0931-T87031-01Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
2409825-32-5
Target
NOD-like Receptor (NLR)
Related Pathways
Immunology/Inflammation
Bioactivity
NP3-562 is a powerful, orally administered tricyclic NLRP3 inhibitor, demonstrating an IC?? of 214 nM. At a dosage of 30 mg/kg given orally (p.o.), NP3-562 effectively suppresses IL-1? release in a mouse model of acute peritonitis [1].
Smiles
C(C)(C)(O)C=1N2C3=C(C=C2C(=O)N(CC(N[C@H]4CN(C)CCC4)=O)N1)SC(Cl)=C3
Molecular Formula
C19H24ClN5O3S
Molecular Weight
437.94
Shipping Conditions
Cool pack
Storage Temperature
-20°C

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