NP3-562

• Target :

  NOD-like Receptor (NLR)

• Related Pathways :

  Immunology/Inflammation

• Bioactivity :

  NP3-562 is a powerful, orally administered tricyclic NLRP3 inhibitor, demonstrating an IC?? of 214 nM. At a dosage of 30 mg/kg given orally (p.o.), NP3-562 effectively suppresses IL-1? release in a mouse model of acute peritonitis [1].

• Smiles :

  C(C)(C)(O)C=1N2C3=C(C=C2C(=O)N(CC(N[C@H]4CN(C)CCC4)=O)N1)SC(Cl)=C3

• Molecular Formula :

  C19H24ClN5O3S

• Molecular Weight :

  437.94

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C

• CAS Number :

  2409825-32-5