Products for Research Use Only

IKZF3 degrader 1

CAT: 0931-T89846-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0931-T89846-01Size:10 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Target
Others, IKZF, Molecular Glues
Related Pathways
Immunology/Inflammation, Others, PROTAC
Bioactivity
IKZF3 Degrader 1 (compound 19a) acts as an effective IKZF3 degrader with an EC50 of 0.012 μM and a minimal yield of 9.2%. It enhances the association of IKZF3 with Cereblon (CRBN), subsequently facilitating the ubiquitination and degradation of IKZF3.
Molecular Formula
C25H18BrCl3N2O5
Molecular Weight
612.68
Shipping Conditions
Ice Packs
Storage Temperature
-20°C