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IKZF2-degrader 1

CAT: 0931-T207476-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0931-T207476-01Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
2983840-43-1
Target
IKZF, Molecular Glues
Related Pathways
Immunology/Inflammation, PROTAC
Bioactivity
IKZF2-degrader 1 (Compound 31) is a molecular glue-type degrader of IKZF2 with a DC50 of 0.5 nM. It exhibits relatively low degradation activity against CK1α, with a DC50 of 210 nM. This compound is applicable in research focused on IKZF2-dependent cancers.
Smiles
O=C1NC(=O)C(N2C(=O)C3=CC=C(C4=NC=5C(=NNC5C(=C4)CN6CCCC6)NC(C)C)C(F)=C3C2)CC1
Molecular Formula
C27H30FN7O3
Molecular Weight
519.57
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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