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SR1555 hydrochloride

CAT: 0931-T89635-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0931-T89635-01Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
2309312-90-9
Bioactivity
SR1555 hydrochloride is the hydrochloride salt form of SR1555. It acts as an inverse agonist for the retinoic acid receptor-related orphan receptor γ (RORγ), with an IC50 of 1 μM. This compound inhibits the development and function of pro-inflammatory TH17 cells while increasing the frequency of anti-inflammatory regulatory T (Treg) cells. SR1555 hydrochloride is utilized in research related to autoimmune diseases.
Smiles
Cl.O=C(N1CCN(CC2=CC=C(C=C2)C=3C=CC(=CC3)C(O)(C(F)(F)F)C(F)(F)F)CC1)C
Molecular Formula
C22H23ClF6N2O2
Molecular Weight
496.87
Shipping Conditions
Ice Packs
Storage Temperature
-20°C