Anticancer agent 249

CAT: 0931-MF-0122334-01Size: 10 mgDry Ice: NoHazardous: No
CAT#:0931-MF-0122334-01Size:10 mg
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PRICE
AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Target
Apoptosis|||HSP
Related Pathways
Apoptosis|||Cytoskeletal Signaling|||Metabolism
Bioactivity
Anticanceragent 249 (Compound 89) is an inhibitor of Hsp90?, exhibiting an IC50 of 16.5 ?M in PC3MM2 cells. It suppresses the proliferation of various cancer cell lines including MCF-7, T47D, MDA-MB-231, MDA-MB-468, and SKBr3, with IC50 values ranging from 1.8 to 5.3 ?M. Additionally, Anticanceragent 249 induces apoptosis in MDA-MB-231 cells and demonstrates antitumor activity in mice.
Shipping Conditions
Cool pack
Storage Temperature
-20°C

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