Products for Research Use Only

INOS/COX-2-IN-3

CAT: 0931-T89228-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0931-T89228-01Size:10 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Target
COX, NO Synthase
Related Pathways
Immunology/Inflammation, Neuroscience
Bioactivity
INOS/COX-2-IN-3 (compound 7d) is a dual inhibitor of iNOS and COX-2, demonstrating potential anti-inflammatory activity in LPS-induced RAW 264.7 cells (IC50=3.48 μM) . This compound exhibits good plasma stability, oral activity, and gastric safety. Its inhibitory effects on iNOS and COX-2 expressions are 5.43 times and 2.37 times higher than those of Indomethacin, respectively.
Shipping Conditions
Ice Packs
Storage Temperature
-20°C