Products for Research Use Only

PBE-AMF

CAT: 0013-GTR19238358-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19238358-01Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
PBE-AMF is a prodrug that activates hydrogen peroxide, selectively inhibiting the proliferation of aggressive MDA-MB-231 breast cancer cells (IC50=6.4 μM) while sparing non-cancerous MCF-10A cells. Its anticancer mechanism involves disrupting DNA synthesis, depleting ATP, inducing apoptosis, and causing cell cycle arrest, making it a candidate for in vitro oncology research.
Field of Research
Cell Biology, Immunology & Inflammation, Metabolism Research, Molecular Biology, Signal Transduction
Storage Conditions
-20°C
Notes
For research use only.

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