PSB-KK1445

• Target:

  Cannabinoid Receptor

• Related Pathways:

  GPCR/G Protein

• Bioactivity:

  PSB-KK1445 is a potent and selective agonist of GPR18, exhibiting EC50 values of 45.4 nM for humans and 124 nM for mice. The selectivity of PSB-KK1445 for GPR18 over the CB receptor subtypes GPR55 and GPR183 exceeds 200-fold.

• Smiles:

  O=C1C2=C(N=C(NCCC3=CNC=4C=CC=CC43)N2CC5=CC=C(F)C=C5)N(C(=O)N1C)C

• Molecular Formula:

  C24H23FN6O2

• Molecular Weight:

  446.48

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  885896-54-8