Anticancer agent 231

• Target :

  ERK

• Related Pathways :

  MAPK

• Bioactivity :

  Anticanceragent 231 (compound P5) is a tyrosine kinase inhibitor with an IC50 value of 3.95 ?M. It targets the EGFR-ERK1/2 signaling pathway, reducing cell viability, proliferation, migration, and cancer stemness in triple-negative breast cancer (TNBC) cells, potentially playing a significant role in the treatment of TNBC.

• Smiles :

  ClC=1C=CC(=CC1)C2=NN(C=3C=CC=CC3)C(C4=CC=C(C=C4)N(C)C)C2

• Molecular Formula :

  C23H22ClN3

• Molecular Weight :

  375.89

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C

• CAS Number :

  128519-30-2