Products for Research Use Only

MT-125

CAT: 0931-T211243-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0931-T211243-01Size:10 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Target
ROS, PDGFR, mTOR, ERK, Myosin, Ferroptosis, Akt
Related Pathways
PI3K/Akt/mTOR signaling, Apoptosis, Immunology/Inflammation, Tyrosine Kinase/Adaptors, MAPK, Angiogenesis, Cytoskeletal Signaling
Bioactivity
MT-125 is a specific and well-tolerated inhibitor of non-muscle myosin IIA [Ki, NMIIA = 2.7 μM] and IIB [EC50 = 1.7 μM]. It can cross the blood-brain barrier and induces ferroptosis and DNA damage by raising reactive oxygen species (ROS) levels within tumor cells. Additionally, MT-125 enhances the PDGFR signaling pathway and is utilized in glioblastoma research.
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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