ATR-258

• Target :

  Adrenergic Receptor

• Related Pathways :

  GPCR/G Protein|||Neuroscience

• Bioactivity :

  ATR-258 is a GRK2-biased partial agonist of ?2AR. It acts as a competitive antagonist of ?1AR and exhibits weak partial agonist activity on ?3AR at a concentration of 10 ?M. ATR-258 enhances glycemic control and reduces lipid accumulation in obese mice with minimal side effects. It is applicable in research on type 2 diabetes (T2DM) .

• Smiles :

  [C@@H](CNC(C)(C)C)(O)C=1C=C(F)C=NC1

• Molecular Formula :

  C11H17FN2O

• Molecular Weight :

  212.26

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C

• CAS Number :

  2301983-88-8