ATR-258

• Target:

  Adrenergic Receptor

• Related Pathways:

  GPCR/G Protein|||Neuroscience

• Bioactivity:

  ATR-258 is a GRK2-biased partial agonist of ?2AR. It acts as a competitive antagonist of ?1AR and exhibits weak partial agonist activity on ?3AR at a concentration of 10 ?M. ATR-258 enhances glycemic control and reduces lipid accumulation in obese mice with minimal side effects. It is applicable in research on type 2 diabetes (T2DM) .

• Smiles:

  [C@@H] (CNC (C) (C) C) (O) C=1C=C (F) C=NC1

• Molecular Formula:

  C11H17FN2O

• Molecular Weight:

  212.26

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  2301983-88-8