ATR-258

CAT: 0931-T210670-01Size: 10 mgDry Ice: NoHazardous: No
CAT#:0931-T210670-01Size:10 mg
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
2301983-88-8
Target
Adrenergic Receptor
Related Pathways
GPCR/G Protein|||Neuroscience
Bioactivity
ATR-258 is a GRK2-biased partial agonist of ?2AR. It acts as a competitive antagonist of ?1AR and exhibits weak partial agonist activity on ?3AR at a concentration of 10 ?M. ATR-258 enhances glycemic control and reduces lipid accumulation in obese mice with minimal side effects. It is applicable in research on type 2 diabetes (T2DM) .
Smiles
[C@@H](CNC(C)(C)C)(O)C=1C=C(F)C=NC1
Molecular Formula
C11H17FN2O
Molecular Weight
212.26
Shipping Conditions
Cool pack
Storage Temperature
-20°C

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