Anticancer agent 214

• Target:

  Topoisomerase

• Related Pathways:

  DNA Damage/DNA Repair

• Bioactivity:

  Anticanceragent 214 (2) is a camptothecin-derived compound with IC50 values of 2.6 nM for MCF-7 cells and 15.7 nM for MDA-MB-231 cells.

• Smiles:

  [C@@H](C)(N)C1=C2C(C=3N(C2)C(=O)C4=C(C3)[C@](CC)(O)C(=O)OC4)=NC=5C1=CC(C)=C(F)C5

• Molecular Formula:

  C23H22FN3O4

• Molecular Weight:

  423.44

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  2916404-95-8