CDK5-IN-4

• Target :

  GSK-3|||CDK

• Related Pathways :

  Cell Cycle/Checkpoint|||PI3K/Akt/mTOR signaling|||Stem Cells

• Bioactivity :

  CDK5-IN-4 (compound 4), a potent type-II multikinase inhibitor, targets CDK5 with an IC 50 of 9.8 ?M. Additionally, it inhibits GSK-3?, GSK-3?, CDK9, and CDK2, demonstrating IC 50 values of 0.98, 4.00, 1.76, and 6.24 ?M, respectively. This compound is applicable in glioblastoma research.

• Smiles :

  N([C@@H]1[C@@]2([C@@]([C@@H](NC(NCC3=CC=CC=C3)=O)CO2)(OC1)[H])[H])C=4N=C(C=CN4)C5=CC(F)=CC=C5

• Molecular Formula :

  C24H24FN5O3

• Molecular Weight :

  449.48

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C

• CAS Number :

  1212711-91-5