Cdk5 Substrate

CAT: 0931-T37207-01Size: 1 mgDry Ice: NoHazardous: No
CAT#:0931-T37207-01Size:1 mg
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CAS Number
164669-07-2
Bioactivity
Cyclin-dependent kinase 5 (Cdk5) is a serine/threonine kinase that is predominantly active in neuronal tissues. With p25 or p35, Cdk5 phosphorylates a range of proteins, including histone H1 and tau. Cdk5 substrate is a synthetic peptide (PKTPKKAKKL) corresponding to a sequence of histone H1. It is phosphorylated by Cdk5 with a Km value of 5 ?M.
Smiles
C([C@@H](NC([C@@H](NC(=O)[C@@H]1CCCN1)CCCCN)=O)[C@@H](C)O)(=O)N2[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@@H](CC(C)C)C(O)=O)=O)CCCCN)=O)CCCCN)=O)C)=O)CCCCN)=O)CCCCN)=O)CCC2
Molecular Formula
C53H99N15O12
Molecular Weight
1138.45
Shipping Conditions
Cool pack
Storage Temperature
-20°C

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