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Cdk5 Substrate acetate

CAT: 0931-T37207L-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0931-T37207L-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Target
CDK
Related Pathways
Cell Cycle/Checkpoint
Purity
0.9621
Bioactivity
Cyclin-dependent kinase 5 (Cdk5) is a serine/threonine kinase that is predominantly active in neuronal tissues. With p25 or p35, Cdk5 phosphorylates a range of proteins, including histone H1 and tau. Cdk5 Substrate acetate is a synthetic peptide (PKTPKKAKKL) corresponding to a sequence of histone H1. It is phosphorylated by Cdk5 with a Km value of 5 μM.
Smiles
CC(O)=O.CC(C)C[C@@H](C(O)=O)NC([C@H](CCCCN)NC([C@H](CCCCN)NC([C@H](C)NC([C@H](CCCCN)NC([C@H](CCCCN)NC([C@H]1N(C([C@H]([C@H](O)C)NC([C@H](CCCCN)NC([C@H]2NCCC2)=O)=O)=O)CCC1)=O)=O)=O)=O)=O)=O
Molecular Formula
C55H103N15O14
Molecular Weight
1198.5
Shipping Conditions
Ice Packs
Storage Temperature
-20°C