Cdk5 Substrate acetate

• Target:

  CDK

• Related Pathways:

  Cell Cycle/Checkpoint

• Purity:

  0.9621

• Bioactivity:

  Cyclin-dependent kinase 5 (Cdk5) is a serine/threonine kinase that is predominantly active in neuronal tissues. With p25 or p35, Cdk5 phosphorylates a range of proteins, including histone H1 and tau. Cdk5 Substrate acetate is a synthetic peptide (PKTPKKAKKL) corresponding to a sequence of histone H1. It is phosphorylated by Cdk5 with a Km value of 5 µM.

• Smiles:

  CC(O)=O.CC(C)C[C@@H](C(O)=O)NC([C@H](CCCCN)NC([C@H](CCCCN)NC([C@H](C)NC([C@H](CCCCN)NC([C@H](CCCCN)NC([C@H]1N(C([C@H]([C@H](O)C)NC([C@H](CCCCN)NC([C@H]2NCCC2)=O)=O)=O)CCC1)=O)=O)=O)=O)=O)=O

• Molecular Formula:

  C55H103N15O14

• Molecular Weight:

  1198.5

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C