EF-4-177

• Target :

  CDK

• Related Pathways :

  Cell Cycle/Checkpoint

• Bioactivity :

  EF-4-177, an orally active, allosteric CDK2 inhibitor, exhibits an IC50 value of 87 nM. It has been shown to disrupt spermatogenesis.

• Smiles :

  [H+].N#CC=1C=CC2=C(C1)NC=C2CCNC3=CC=[C-](C=C3C(=O)[O-])[S+6]([F-])([F-])([F-])([F-])[F-]

• Molecular Formula :

  C18H14F5N3O2S

• Molecular Weight :

  431.38

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C

• CAS Number :

  2891574-93-7