CDK12-IN-7

• Target:

  CDK

• Related Pathways:

  Cell Cycle/Checkpoint

• Bioactivity:

  CDK12-IN-7 (Compound 2), a dual inhibitor of CDK12 and CDK2, exhibits IC 50 values of 42 nM and 196 nM, respectively. This compound demonstrates anti-cell proliferation properties, making it applicable in cancer research.

• Smiles:

  CN1C=2N(C=3C(N2)=NC(N(C(NCC4=CC=CC=C4)=O)[C@@H]5CC[C@@H](NC=6N=C(OC7COC7)C(C(F)(F)F)=CN6)CC5)=CC3)C=CC1=O

• Molecular Formula:

  C32H32F3N9O4

• Molecular Weight:

  663.65

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  3033863-94-1