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CDK12-IN-6

CAT: 0013-GTR19188551Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19188551Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
CDK12-IN-6 is a potent and selective pyrazolotriazine-based CDK12 inhibitor (IC50 = 1.19 μM at 2 mM ATP), exhibiting >20-fold selectivity over CDK2 and CDK9. It serves as a valuable chemical probe for oncology research, particularly in studying transcription-associated mechanisms in cancers such as ovarian and prostate carcinomas.
CAS Number
2651196-71-1
Field of Research
Cell Biology, Signal Transduction
Smiles
Fc1ccc2nc (CNc3nc (nc4c (cnn34) C3CC3) N3CCNCC3) [nH]c2c1F
Molecular Formula
C20H21F2N9
Molecular Weight
425.448
Storage Conditions
-20°C
Notes
For research use only.

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