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Pan-KRAS-IN-6

CAT: 0013-GTR19234216-01Size: 25 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19234216-01Size:25 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Pan-KRAS-IN-6 (compound 12) is a high-potency pan-KRAS inhibitor, demonstrating single-digit nanomolar IC50 values against the G12D (9.79 nM) and G12V (6.03 nM) oncogenic mutants. This small molecule is a valuable research tool for investigating KRAS-driven cancers in both cellular and animal model systems.
CAS Number
3033565-36-2
Field of Research
Pharmacology & Drug Discovery, Signal Transduction
Smiles
C (OC=1N=C (C2=C (N1) C (F) =C (C (Cl) =C2) C3=C4C (SC (N) =N4) =C (F) C=C3) N5CC (C) (O) COCC5) [C@@]67N (C[C@H] (F) C6) CCC7
Molecular Formula
C29H30ClF3N6O3S
Molecular Weight
635.10
Storage Conditions
-20°C
Notes
For research use only.

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