POP-3MB

• Target:

  ERK|||Transferase

• Related Pathways:

  MAPK|||Metabolism

• Bioactivity:

  POP-3MB (compound 1b) acts as an inhibitor of ICMT, displaying an IC50 value of 2.5 ?M. This compound not only alters the subcellular localization of K-Ras but also impedes Ras activation and inhibits Erk phosphorylation [1].

• Smiles:

  O (C1=C (C (N[C@@H] (CSCC=C (CCC2=CC=C (C=C2) C3=CC=CC=C3) CC=C (C) C) C (O) =O) =O) C=CC=C1) C4=CC=CC=C4

• Molecular Formula:

  C38H39NO4S

• Molecular Weight:

  605.79

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  1144114-27-1