POP-3MB

• Target :

  ERK|||Transferase

• Related Pathways :

  MAPK|||Metabolism

• Bioactivity :

  POP-3MB (compound 1b) acts as an inhibitor of ICMT, displaying an IC50 value of 2.5 ?M. This compound not only alters the subcellular localization of K-Ras but also impedes Ras activation and inhibits Erk phosphorylation [1].

• Smiles :

  O(C1=C(C(N[C@@H](CSCC=C(CCC2=CC=C(C=C2)C3=CC=CC=C3)CC=C(C)C)C(O)=O)=O)C=CC=C1)C4=CC=CC=C4

• Molecular Formula :

  C38H39NO4S

• Molecular Weight :

  605.79

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C

• CAS Number :

  1144114-27-1