POP-3MB

CAT: 0931-T87237-01Size: 10 mgDry Ice: NoHazardous: No
CAT#:0931-T87237-01Size:10 mg
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CAS Number
1144114-27-1
Target
ERK|||Transferase
Related Pathways
MAPK|||Metabolism
Bioactivity
POP-3MB (compound 1b) acts as an inhibitor of ICMT, displaying an IC50 value of 2.5 ?M. This compound not only alters the subcellular localization of K-Ras but also impedes Ras activation and inhibits Erk phosphorylation [1].
Smiles
O(C1=C(C(N[C@@H](CSCC=C(CCC2=CC=C(C=C2)C3=CC=CC=C3)CC=C(C)C)C(O)=O)=O)C=CC=C1)C4=CC=CC=C4
Molecular Formula
C38H39NO4S
Molecular Weight
605.79
Shipping Conditions
Cool pack
Storage Temperature
-20°C

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