POP-IN-2

CAT: 0804-HY-143475Size: 1 EachDry Ice: NoHazardous: No
CAT#:0804-HY-143475Size:1 Each
Selected
PRICE
AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Product image 1
1 / 1
Description
POP-IN-2 (Compound 7k) is a potent, covalent prolyl oligopeptidase (POP) inhibitor with a Ki of 6 nM. POP-IN-2 can be used for studying neurodegenerative diseases and cancer[1].
CAS Number
[2743432-81-5]
UNSPSC
12352005
Target
Prolyl Endopeptidase (PREP)
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Cancer-programmed cell death
Field of Research
Cancer; Neurological Disease
Assay Protocol
https://www.medchemexpress.com/pop-in-2.html
Solubility
10 mM in DMSO
Smiles
CC(NC1=CC=C(C(N2C(B3O[C@@]4([H])[C@@]([C@](C5)([H])C(C)(C)[C@]5([H])C4)(C)O3)CCC2)=O)C(OC)=C1)=O
Molecular Formula
C24H33BN2O5
Molecular Weight
440.34
References & Citations
[1]Jessica Plescia, et al. Discovery of covalent prolyl oligopeptidase boronic ester inhibitors. Eur J Med Chem. 2020 Jan 1;185:111783.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

Related Products

CatalogName
HY-143474POP-IN-3
HY-149710POP-3MB
HY-146667POP-IN-1
HY-W011060-01Cryptand 2.2.2
HY-B1500-012,2,2-Trichloroethanol
HY-N13185POPi
HY-N2048-012,2':5',2''-Terthiophene
HY-W0733142,2,2-Trifluoroethoxyamine (hydrochloride)
HY-B1500R-012,2,2-Trichloroethanol (Standard)
HY-132268-01Cav 2.2 blocker 2

Alternative Products

CatalogName
MBS5805216POP-IN-2
A10Z53Recombinant Pop n 2
MBS5804599POP-IN-1
MF-0121199-01POP-3MB
MBS1174320-01Recombinant Caenorhabditis briggsae Protein pop-1 (pop-1)
C2086Stop-Pop™ CapLock
GWB-911136POP assay kit
A78596-50ULpop-1 Antibody
MBS1425526-01Recombinant Caenorhabditis elegans Protein pop-1 (pop-1)
MBS668515-01Polyclonal Antibody to ASC2 (ASC-2/POP)

Popular Products