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PI3Kα-IN-16

CAT: 0931-T87160-01Size: 100 mgDry Ice: NoHazardous: No
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CAT#:0931-T87160-01Size:100 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
1448711-61-2
Target
PI3K, Wnt/beta-catenin
Related Pathways
PI3K/Akt/mTOR signaling, Stem Cells, Cytoskeletal Signaling
Bioactivity
PI3Kα-IN-16 (Z86) is a recently developed inhibitor of PI3Kα, displaying an IC 50 of 4.28 μM. With potent efficacy, it inhibits the growth and migration of CRCs mediated by PI3K. Additionally, PI3Kα-IN-16 also suppresses the Wnt signaling pathway [1].
Smiles
C(C)N1C=2C(C=3C1=CC=CC3)=CC(C(OC(C)C)=O)=NC2C=4C5=C(C=CC4)C=CC=C5
Molecular Formula
C27H24N2O2
Molecular Weight
408.49
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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