PI3Kα-IN-15

CAT: 0931-T87159-01Size: 100 mgDry Ice: NoHazardous: No

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CAT#:0931-T87159-01Size:100 mg

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24/48H Stock Items & 2 to 6 Weeks non Stock Items.

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CAS Number

2893920-80-2

Target

PI3K

Related Pathways

PI3K/Akt/mTOR signaling

Bioactivity

PI3Kα-IN-15 is a powerful inhibitor of PI3Kα, exhibiting an IC50 of 0.15 μM. It shows promising anti-proliferative effects, inhibiting the growth of SKOV-3, T47D, NCI-H1975, NCI-H460, and MCF-7 cell lines with respective IC50 values of 26.6 μM, 7.9 μM, 32.1 μM, 17.7 μM, and 9.4 μM. This compound is useful for cancer research [1].

Smiles

C(=O)(C=1N=C2C(=CC(C)=CN2C1)C=3C=C(NS(=O)(=O)C4=CC=C(F)C=C4)C(OC)=NC3)N5CCCC5

Molecular Formula

C25H24FN5O4S

Molecular Weight

509.55

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

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