PFI-6

• Bioactivity :

  PFI-6 is a selective and non-cytotoxic probe targeting the YEATS domain of MLLT1 (ENL/YEATS1) and MLLT3 (AF9/YEATS3), with IC50 values of 140 nM for MLLT1 and 160 nM for MLLT3. It serves as a molecular tool to investigate the role of MLLT1/3 in diseases and genome validation studies [1].

• Smiles :

  N(C(=O)C=1C=C(ON1)C2=CC(O)=C(C(N(C)C)=O)C=C2)[C@H]3C=4C(CC3)=CC=CC4

• Molecular Formula :

  C22H21N3O4

• Molecular Weight :

  391.42

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C

• CAS Number :

  2675452-91-0