PFI-2

• Target:

  Histone Methyltransferase

• Related Pathways:

  Chromatin/Epigenetic

• Purity:

  0.9938

• Bioactivity:

  PFI-2 is an effective, specific and cell-active lysine methyltransferase SETD7 inhibitor (Ki/IC50: 0.33/2 nM), 1000-fold selectivity over other methyltransferases and other non-epigenetic targets.

• Smiles:

  FC1=C2C(=CC(S(N[C@H](CC3=CC(C(F)(F)F)=CC=C3)C(=O)N4CCCC4)(=O)=O)=C1)CCNC2

• Molecular Formula:

  C23H25F4N3O3S

• Molecular Weight:

  499.52

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  1627676-59-8