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JTE-952

CAT: 0931-T11729-01Size: 25 mgDry Ice: NoHazardous: No
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CAT#:0931-T11729-01Size:25 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
1255303-54-8
Target
C-Fms, Histamine Receptor
Related Pathways
Neuroscience, GPCR/G Protein, Tyrosine Kinase/Adaptors, Immunology/Inflammation
Bioactivity
JTE-952 is a oral, potent active and selective Type II inhibitor of colony stimulating factor-1 receptor (CSF-1R or cFMS, type III receptor tyrosine kinase), with IC50 values of 13 nM and 261 nM for CSF1R and TrkA , respectively. Effective against a mouse collagen-induced model of arthritis.
Smiles
C(=O)(N1CC(C1)C2=CC(OC)=C(OCC3=CC=C(C=C3)C4CC4)C=C2)C5=CC(COC[C@H](CO)O)=CC=N5
Molecular Formula
C30H34N2O6
Molecular Weight
518.6
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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BA8858-10JTE-952
BJ168569-01JTE 952
A18391-100JTE-952 100mg
A18391-5JTE-952 5mg
A18391-50JTE-952 50mg
A18391-25JTE-952 25mg
A18391-10JTE-952 10mg
GTR19249039-01MRK-952
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