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HSD17B13-IN-64

CAT: 0931-T86654-01Size: 25 mgDry Ice: NoHazardous: No
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CAT#:0931-T86654-01Size:25 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
2770247-34-0
Target
Dehydrogenase
Related Pathways
Metabolism
Bioactivity
HSD17B13-IN-64 (Compound 143), an inhibitor of hydroxysteroid 17β-dehydrogenase 13 (HSD17B13), exhibits a potent IC50 value of ≤ 0.1 μM against estradiol. This compound has applications in the study of various diseases, including liver conditions like NAFLD and NASH, metabolic and cardiovascular disorders, as well as drug-induced liver injury (DILI) [1].
Smiles
N(C(=O)C1=CC(Cl)=C(O)C(Cl)=C1)C2=C3C(N=CN(CC4=C(Cl)C=CC=N4)C3=O)=CC=C2
Molecular Formula
C21H13Cl3N4O3
Molecular Weight
475.71
Shipping Conditions
Ice Packs
Storage Temperature
-20°C