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HSD17B13-IN-57

CAT: 0931-T86646-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0931-T86646-01Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
2770246-86-9
Target
Dehydrogenase
Related Pathways
Metabolism
Bioactivity
HSD17B13-IN-57 (Compound 93) acts as an inhibitor targeting hydroxysteroid 17β-dehydrogenase 13 (HSD17B13), demonstrating an IC 50 of ≤ 0.1 μM against estradiol. This compound is applicable in the study of various health conditions, including liver, metabolic, and cardiovascular diseases—specifically NAFLD, NASH—and drug-induced liver injury (DILI) [1].
Smiles
N(C(=O)C1=CC(Cl)=C(O)C(Cl)=C1)C2=C3C(N(C)C(=O)N(CC4=C(OC(F)(F)F)C=CC=C4)C3=O)=CC=C2
Molecular Formula
C24H16Cl2F3N3O5
Molecular Weight
554.3
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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