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HSD17B13-IN-27

CAT: 0931-T86616-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0931-T86616-01Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
2758802-31-0
Target
Dehydrogenase
Related Pathways
Metabolism
Bioactivity
HSD17B13-IN-27 (compound 30) serves as a potent inhibitor of hydroxysteroid 17?-dehydrogenase 13 (HSD17B13), exhibiting an IC50 of less than 0.1 μM and approximately less than 1 μM for estradiol and Leukotriene B3, respectively, as substrates. This compound is crucial in the management of nonalcoholic fatty liver diseases (NAFLDs), including nonalcoholic steatohepatitis (NASH) [1].
Smiles
C(NCCC1=C(OC)C=CC=C1)(=O)C2=C(NC(=O)C3=CC(F)=C(O)C=C3)C=CS2
Molecular Formula
C21H19FN2O4S
Molecular Weight
414.45
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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