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DYB-03

CAT: 0931-T86312-01Size: 25 mgDry Ice: NoHazardous: No
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CAT#:0931-T86312-01Size:25 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
2982792-85-6
Target
Histone Methyltransferase, HIF/HIF Prolyl-Hydroxylase
Related Pathways
Chromatin/Epigenetic, Metabolism
Bioactivity
DYB-03 is an orally active HIF-1α/EZH2 inhibitor that inhibits migration, invasion, and angiogenesis of lung cancer cells and HUVECs in vitro and in vivo, and induces apoptosis in 2-ME2- and GSK126-resistant A549 and H460 cells [1].
Smiles
OC1=C2C(=CC=C1C(/C=C/C3=CC(OCCCN4CCOCC4)=C(OC)C=C3)=O)OC(C)(C)C=C2
Molecular Formula
C28H33NO6
Molecular Weight
479.56
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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