DYB-03

• Target :

  Histone Methyltransferase|||HIF/HIF Prolyl-Hydroxylase

• Related Pathways :

  Chromatin/Epigenetic|||Metabolism

• Bioactivity :

  DYB-03 is an orally active HIF-1?/EZH2 inhibitor that inhibits migration, invasion, and angiogenesis of lung cancer cells and HUVECs in vitro and in vivo, and induces apoptosis in 2-ME2- and GSK126-resistant A549 and H460 cells [1].

• Smiles :

  OC1=C2C(=CC=C1C(/C=C/C3=CC(OCCCN4CCOCC4)=C(OC)C=C3)=O)OC(C)(C)C=C2

• Molecular Formula :

  C28H33NO6

• Molecular Weight :

  479.56

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C

• CAS Number :

  2982792-85-6