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COP1-ATGL modulator 1

CAT: 0931-T86073-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0931-T86073-01Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
2946701-09-1
Target
E1/E2/E3 Enzyme, Lipase, Others
Related Pathways
Metabolism, Others, Ubiquitination
Bioactivity
COP1-ATGL modulator 1 (86) is an orally active compound that targets the COP1-ATGL axis. It enhances ATGL protein expression, decreases ATGL ubiquitination and COP1 autoubiquitination, and notably reduces lipid accumulation in hepatocytes, effective in the nanomolar concentration [1].
Smiles
C(CN1CCCCC1)N2C=3C(C(=O)N(CCOC)C2=O)=CC(NC(NC4=CC(C(C)=O)=CC=C4)=O)=CC3
Molecular Formula
C27H33N5O5
Molecular Weight
507.58
Shipping Conditions
Ice Packs
Storage Temperature
-20°C