CDK2-IN-12

• Target:

  Carbonic Anhydrase|||Others|||CDK

• Related Pathways:

  Metabolism|||Others|||Cell Cycle/Checkpoint

• Bioactivity:

  CDK2-IN-12 (compound 10b) is a potent inhibitor of CDK2 (IC50: 11.6 ?M) and exhibits inhibition of hCA subtypes I, II, IX, and XII with KI values of 3534, 638.4, 44.3, and 48.8 nM, respectively. Additionally, CDK2-IN-12 shows anti-cancer effects.

• Smiles:

  N(=N/C1=CC=C(S(N)(=O)=O)C=C1)\C2=C3N(C(N)=C(C#N)C(=N3)C4=CC=C(C)C=C4)N=C2N

• Molecular Formula:

  C20H17N9O2S

• Molecular Weight:

  447.47

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  2410402-88-7