CDK2-IN-12

• Target :

  Carbonic Anhydrase|||Others|||CDK

• Related Pathways :

  Metabolism|||Others|||Cell Cycle/Checkpoint

• Bioactivity :

  CDK2-IN-12 (compound 10b) is a potent inhibitor of CDK2 (IC50: 11.6 ?M) and exhibits inhibition of hCA subtypes I, II, IX, and XII with KI values of 3534, 638.4, 44.3, and 48.8 nM, respectively. Additionally, CDK2-IN-12 shows anti-cancer effects.

• Smiles :

  N(=N/C1=CC=C(S(N)(=O)=O)C=C1)\C2=C3N(C(N)=C(C#N)C(=N3)C4=CC=C(C)C=C4)N=C2N

• Molecular Formula :

  C20H17N9O2S

• Molecular Weight :

  447.47

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C

• CAS Number :

  2410402-88-7