BIO-7488

• Target :

  IRAK

• Related Pathways :

  Immunology/Inflammation|||NF-?B

• Bioactivity :

  BIO-7488, a potent and selective IRAK4 inhibitor, is orally active and penetrates the CNS, exhibiting an IC50 of 0.6 nM for IRAK4 and > 30 ?M for hERG [1].

• Smiles :

  CC12CC(C1)(CO2)C=3N=C4N(C3)C=C(C(NC5=C6N(N=C5)C=C(C)C=N6)=O)C(OC(C)C)=N4

• Molecular Formula :

  C23H25N7O3

• Molecular Weight :

  447.49

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C

• CAS Number :

  2573211-25-1