BIO-2007817

• Target :

  PTEN|||E1/E2/E3 Enzyme|||DNA/RNA Synthesis|||Antibacterial

• Related Pathways :

  Ubiquitination|||Cell Cycle/Checkpoint|||DNA Damage/DNA Repair|||PI3K/Akt/mTOR signaling|||Microbiology/Virology

• Bioactivity :

  BIO-2007817 is a positive allosteric modulator (PAM) of Parkin, an E3 ubiquitin ligase. This compound enhances the activity of wild-type Parkin, stimulates Parkin's autoubiquitination, and induces the appearance of mono-ubiquitinated forms of Miro1 (a Parkin substrate) with an EC50 of 0.17 ?M.

• Molecular Formula :

  C32H36N6O3

• Molecular Weight :

  552.67

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C