Anticancer agent 194

• Target:

  Reactive Oxygen Species|||Ferroptosis|||Autophagy

• Related Pathways:

  Autophagy|||Immunology/Inflammation|||NF-?B|||Metabolism|||Apoptosis

• Bioactivity:

  Anticancer agent 194 (compound 10p), a ferroptosis and autophagy inducer, arrests the colon cancer cell cycle at the G2/M phase without inducing apoptosis, and independently triggers cell ferroptosis and autophagy through the massive accumulation of ROS [1].

• Smiles:

  O=C(NCCCl)N1C2=CC=C(OC)C=C2NCC1

• Molecular Formula:

  C12H16ClN3O2

• Molecular Weight:

  269.73

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  2767204-90-8