Anticancer agent 188

• Target :

  Reactive Oxygen Species|||DNA/RNA Synthesis

• Related Pathways :

  DNA Damage/DNA Repair|||Cell Cycle/Checkpoint|||Metabolism|||Immunology/Inflammation|||NF-?B

• Bioactivity :

  Compound D43 (Anticancer agent 188) inhibits DNA synthesis in TNBC cells, causing cell cycle arrest at the G2/M phase. It exhibits anticancer properties by inducing ROS-mediated apoptosis and DNA damage [1].

• Smiles :

  O=C1N=C2C(=NC(=NN2C)C3=CC=CC=C3F)C(=O)N1C

• Molecular Formula :

  C13H10FN5O2

• Molecular Weight :

  287.25

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C

• CAS Number :

  1207377-56-7