AB-452

• Target:

  HBV

• Related Pathways:

  Microbiology/Virology

• Bioactivity:

  AB-452, a dihydroquinolizinone (DHQ) analogue, is a potent and orally active HBV RNA destabilizer that inhibits PAPD5/7 proteins in vitro and demonstrates good in vivo efficacy in a chronic HBV mouse model [1].

• Smiles:

  [C@@H](C)(C)[C@H]1N2C(C=3C(C1)=CC(OCCCOC)=C(OC)N3)=CC(=O)C(C(O)=O)=C2

• Molecular Formula:

  C21H26N2O6

• Molecular Weight:

  402.44

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  2226178-35-2