AB-452

• Target :

  HBV

• Related Pathways :

  Microbiology/Virology

• Bioactivity :

  AB-452, a dihydroquinolizinone (DHQ) analogue, is a potent and orally active HBV RNA destabilizer that inhibits PAPD5/7 proteins in vitro and demonstrates good in vivo efficacy in a chronic HBV mouse model [1].

• Smiles :

  [C@@H](C)(C)[C@H]1N2C(C=3C(C1)=CC(OCCCOC)=C(OC)N3)=CC(=O)C(C(O)=O)=C2

• Molecular Formula :

  C21H26N2O6

• Molecular Weight :

  402.44

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C

• CAS Number :

  2226178-35-2