Products for Research Use Only
RegisterLogin

CRBN ligand-452

CAT: 0804-HY-W953212Size: 1 EachDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0804-HY-W953212Size:1 Each
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
CRBN ligand-452 is an E3 ubiquitin ligase cereblon (CRBN) ligand used to recruit the cereblon protein. CRBN ligand-452 can be linked to a target protein ligand via a linker to form a PROTAC.
CAS Number
2925086-13-9
UNSPSC
12352005
Hazard Statement
H302-H315-H319-H335
Target
Ligands for E3 Ligase
Related Pathways
PROTAC
Field of Research
Cancer
Smiles
O=CC1=NN=CC=2C=CC(=CC12)N3C(=O)NC(=O)CC3
Molecular Formula
C13H10N4O3
Molecular Weight
270.25
Precautions
P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
Cereblon

Chemical Information

7-(2,4-Dioxo-1,3-diazinan-1-yl)phthalazine-1-carbaldehyde
CAS Number2925086-13-9
PubChem CID169548588
IUPAC Name7-(2,4-dioxo-1,3-diazinan-1-yl)phthalazine-1-carbaldehyde
Molecular FormulaC13H10N4O3
Molecular Weight270.24
XLogP-0.4
Topological Polar Surface Area92.3
Hydrogen Bond Donor Count1
Hydrogen Bond Acceptor Count5
Rotatable Bond Count2
Heavy Atom Count20
Formal Charge0
Complexity428
SMILES
C1CN(C(=O)NC1=O)C2=CC3=C(N=NC=C3C=C2)C=O
InChI
InChI=1S/C13H10N4O3/c18-7-11-10-5-9(2-1-8(10)6-14-16-11)17-4-3-12(19)15-13(17)20/h1-2,5-7H,3-4H2,(H,15,19,20)
InChIKey
MMJSWBZJBJXIMF-UHFFFAOYSA-N
Chemical Structure
2D Structure
2D structure of 7-(2,4-Dioxo-1,3-diazinan-1-yl)phthalazine-1-carbaldehyde
CAS: 2925086-13-9
CID: 169548588
Formula: C13H10N4O3
MW: 270.24
Interactive 3D Structure
Loading 3D structure...
View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight270.24
XLogP3-0.4
Hydrogen Bond Donor Count1
Hydrogen Bond Acceptor Count5
Rotatable Bond Count2
Exact Mass270.07529019
Monoisotopic Mass270.07529019
Topological Polar Surface Area92.3 Ų
Heavy Atom Count20
Formal Charge0
Complexity428
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes

Related Products

CatalogName
HY-171224CRBN ligand-45
HY-170213CRBN ligand-183
HY-170108CRBN ligand-47
HY-170075CRBN ligand-16
HY-W953523CRBN ligand-693
HY-W953518CRBN ligand-494
HY-W953514CRBN ligand-540
HY-W953511CRBN ligand-493
HY-W953508CRBN ligand-293
HY-W953505CRBN ligand-350

Alternative Products

CatalogName
GTR19275370-01CRBN ligand-452
T205631-01CRBN ligand-112
T205588-01CRBN ligand-110
T205577-01CRBN ligand-45
T205145-01CRBN ligand-47
T9360-01CRBN ligand-9
GTR19249891-01CRBN ligand-16
GTR19249567-01CRBN ligand-148
GTR19249350-01CRBN ligand-14
GTR19249319-01CRBN ligand-164

Popular Products