BIBO3304 diTFA

• Target:

  Others|||Neuropeptide Y Receptor

• Related Pathways:

  GPCR/G Protein|||Others|||Neuroscience

• Bioactivity:

  BIBO3304 (diTFA), a selective neuropeptide Y (NPY) Y1 receptor antagonist, demonstrates oral efficacy. It exhibits high affinity for Y1 receptors in both humans and rats, with IC50 values of 0.38 nM and 0.72 nM, respectively. Additionally, BIBO3304 (diTFA) enhances bone-tendon healing via the Wnt/?-catenin signaling pathway [1] [2] [3].

• Smiles:

  C(C(O)=O)(F)(F)F.C(C(N[C@@H](C(NCC1=CC=C(CNC(N)=O)C=C1)=O)CCCNC(=N)N)=O)(C2=CC=CC=C2)C3=CC=CC=C3

• Molecular Formula:

  C33H37F6N7O7

• Molecular Weight:

  757.68

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  2310085-85-7