FTI-2148 diTFA

• Target:

  Others|||Transferase

• Related Pathways:

  Metabolism|||Others

• Bioactivity:

  FTI-2148 diTFA, a dual inhibitor targeting both farnesyl transferase (FT-1) and geranylgeranyl transferase-1 (GGT-1), functions as a RAS C-terminal mimetic. It exhibits potent inhibitory capabilities with IC50 values of 1.4 nM for FT-1 and 1.7 ?M for GGT-1, respectively.

• Smiles:

  OC(=O)C(F)(F)F.CSCC[C@H](NC(=O)c1ccc(CNCc2cnc[nH]2)cc1-c1ccccc1C)C(O)=O

• Molecular Formula:

  C26H29F3N4O5S

• Molecular Weight:

  566.6

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  817586-01-9