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NOX2-IN-2 diTFA

CAT: 0931-T200709-01Size: 25 mgDry Ice: NoHazardous: No
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CAT#:0931-T200709-01Size:25 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
2648709-80-0
Target
NADPH
Related Pathways
Metabolism
Bioactivity
NOX2-IN-2 diTFA (compound 33) is an effective inhibitor of NOX2, targeting the p47phox-p22phox protein-protein interaction with a Ki of 0.24 μM. This compound effectively suppresses the production of ROS generated by NOX2 in cells.
Smiles
O=C(C(F)(F)F)O.NC1=CC=C2C(C=CC(OCC3=CN(CCOCCOC4=CC5=CC=C(N)N=C5C=C4)N=N3)=C2)=N1.O=C(C(F)(F)F)O
Molecular Formula
C29H27F6N7O7
Molecular Weight
699.56
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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