NOX2-IN-2 diTFA

• Target:

  NADPH

• Related Pathways:

  Metabolism

• Bioactivity:

  NOX2-IN-2 diTFA (compound 33) is an effective inhibitor of NOX2, targeting the p47phox-p22phox protein-protein interaction with a Ki of 0.24 ?M. This compound effectively suppresses the production of ROS generated by NOX2 in cells.

• Smiles:

  O=C(C(F)(F)F)O.NC1=CC=C2C(C=CC(OCC3=CN(CCOCCOC4=CC5=CC=C(N)N=C5C=C4)N=N3)=C2)=N1.O=C(C(F)(F)F)O

• Molecular Formula:

  C29H27F6N7O7

• Molecular Weight:

  699.56

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  2648709-80-0